Scientists of the Center for Thrombosis and Hemostasis (CTH), the dermatology clinic and the immunology of the University Medical Center Mainz have achieved new findings about the mechanisms of dissolving blood clots (Thrombus). They were able to Show for the first time, that the Effector-Memory-T-Cells, a specialized subgroup of the so called adaptive immune cells, invade into blood clots and cause inflammations. As a result the resolution of the blood clot delays.
The research findings could lead to an improved therapy of the disrupted cardiovascular system.
The research findings were published in the paper “Innate Effector-Memory T-Cell Activation Regulates Post-Thrombotic Vein Wall Inflammation and Thrombus Resolution” in the renowned Journal „Circulation Research“.
Treatment of Thrombosis: Therapeutic benefit of T-Cells
University Medical Center Mainz has achieved new findings about the role of memory cells of the immune defence at dissolving blood clots.