A new study of cardiologists from Mainz reevaluates the role of the vasodilative substance.
A Research Group headed up by Univ.-Prof. Dr. Andreas Daiber of the University Medical Center Mainz detected new side effects of the organic nitrate Nitroglycerin. These could affect the prognosis of treated patients on a long-lasting way. As the recent Study of Mainz shows, a multi-day treatment with nitroglycerin can lead to a damage of the DNA. This could lead to a dying of stem cells, which are important for the repairing processes, as well as of endothelial cells. The latter form the separating layer between blood stream and the surrounding tissue. The recent publication appeared in the scientific journal “Basic Research in Cardiology”.