Selected publications in 2018:
Bohn T, Rapp S, Luther N, Klein M, Bruehl TJ, Kojima N, Aranda Lopez P, Hahlbrock J, Muth S, Endo S, Pektor S, Brand A, Renner K, Popp V, Gerlach K, Vogel D, Lueckel C, Arnold-Schild D, Pouyssegur J, Kreutz M, Huber M, Koenig J, Weigmann B, Probst HC, von Stebut E, Becker C, Schild H, Schmitt E, and Bopp T. Tumor immunoevasion via acidosis dependent induction of regulatory tumor-associated macrophages. Nat Immunol. 2018; 19(12):1319-1329. doi: 10.1038/s41590-018-0226-8.
Ellwardt, E., Pramanik, G., Luchtman, D., Novkovic T, Jubal ER, Vogt J, Arnoux I, Vogelaar CF, Mandal S, Schmalz M, Barger Z, Ruiz de Azua I, Kuhlmann T, Lutz B, Mittmann T, Bittner S, Zipp F, Stroh A. Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis. Nat Neurosci. 2018; 21, 1392–1403. doi:10.1038/s41593-018-0193-2.
Buehler U, Schulenburg K, Yurugi H, Šolman M, Abankwa D, Ulges A, Tenzer S, Bopp T, Thiede B, Zipp F, Rajalingam K. Targeting Prohibitins at the Cell Surface Prevents Th17-mediated Autoimmunity. EMBO J. 2018 Aug 15; 37(16): e99429. doi: 10.15252/embj.201899429
Lacher SM, Thurm C, Distler U, Mohebiany AN, Israel N, Kitic M, Ebering A, Tang Y, Klein M, Wabnitz GH, Wanke F, Samstag Y, Bopp T, Kurschus FC, Simeoni L, Tenzer S, Waisman A. NF-κB inducing kinase (NIK) is an essential post-transcriptional regulator of T-cell activation affecting F-actin dynamics and TCR signaling. J Autoimmun. 2018 Nov;94:110-121. doi: 10.1016/j.jaut.2018.07.017
Echchannaoui H, Petschenka J, Antunes Ferreira E, Hauptrock B, Lotz-Jenne C, Voss RH,Theobald M. A potent tumor-reactivep53-specific single-chain TCR without on-or off-target autoimmunity in vivo. Molecular Therapy. 2018;27(1):261-71. doi: 10.1016/j.ymthe.2018.11.006
Lang-Yona N, Kunert AT, Vogel L, Kampf CJ,Bellinghausen I, Saloga J, Schink A, Ziegler K, Lucas K, Schuppan D, Pöschl U, Weber B, Fröhlich-Nowoisky J. Fresh water, marine and terrestrial cyanobacteria display distinct allergen characteristics. Sci Total Environ. 2018; 612:767-74. doi: 10.1016/j.scitotenv.2017.08.069
Tonigold M, Simon J, Estupiñán D, Kokkinopoulou M, Reinholz J, Kintzel U, Kaltbeitzel A, Renz P, Domogalla MP, Steinbrink K, Lieberwirth I, Crespy D, Landfester K, Mailänder V. Pre-adsorption of antibodies enables targeting of nanocarriers despite a biomolecular corona. Nat Nanotechnol. 2018;13(9):862-869. doi: 10.1038/s41565-018-0171-6
Bros M, Nuhn L, Simon J, Moll L, Mailänder V, Landfester K, Grabbe S. The Protein Corona as a Confounding Variable of Nanoparticle-Mediated Targeted Vaccine Delivery. Front Immunol. 2018;9:1760. doi: 10.3389/fimmu.2018.01760
Hajek E., Krebs F., Bent R., Haas K., Bast A., Steinmetz I., Tuettenberg A., Grabbe S., Bros M. BRAF inhibitors stimulate inflammasome activation and interleukin 1 beta production in dendritic cells. Oncotarget. 2018; 9: 28294-28308. doi: 10.18632/oncotarget.25511
Kröller-Schön S, Daiber A, Steven S, Oelze M, Frenis K, Kalinovic S, Heimann A, Schmidt FP, Pinto A, Kvandova M, Vujacic-Mirski K, Filippou K, Dudek M, Bosmann M, Klein M, Bopp T, Hahad O, Wild PS, Frauenknecht K, Methner A, Schmidt ER, Rapp S, Mollnau H, Münzel T. Crucial role for Nox2 and sleep deprivation in aircraft noise-induced vascular and cerebral oxidative stress, inflammation, and gene regulation. Eur Heart J. 2018 Oct 7;39(38):3528-3539. doi: 10.1093/eurheartj/ehy333