* corresponding author # shared first authorship
--2024-- | ||||||
-Originals- | -Reviews- | |||||
164. | He Y.-M., Burkard, A., Wu, C.-S., Jin, X.-Y., Liu, L., Helm, M., Cheng, L.*, A Direct Chemical Repair of Etheno-Type RNA Damages, (2024), Angew Chem Int Ed Engl., Nov. 26, Online ahead of print, Full text | R27 | Helm, M., Winz, M.-L., Nascent mRNA damage: depot and disposal, (2024), Signal Transduct Target Ther., Aug. 9, 9(1):198, Full text | |||
PMID: 39589841 IF: 16.1 | PMID: 39117645 IF: 40.8 | |||||
163. | Dietrich, V., Alagna, N., Helm, M., Gerber, S., Butto, T., Pod5Viewer: a GUI for inspecting raw nanopore sequencing data, (2024), Bioinformatics, Nov. 28, 40(12):btae665, Full text | R26 | Motorin, Y., Helm, M., General Principles and Limitations for Detection of RNA Modifications by Sequencing, (2024), Acc Chem Res., Feb. 6, 57(3):275-288, Full text | |||
PMID: 39657315 IF: 6.9 | PMID: 38065564 IF: 24.5 | |||||
162. | Kilz, L.-M., Zimmermann, S., Marchand, V., Bourguignon, V., Sudol, C., Brégeon, D., Hamdane, D., Motorin, Y., Helm, M.*, Differential redox sensitivity of tRNA dihydrouridylation, (2024), Nucleic Acid Res., Oct. 26, 52(21):12784-12797, Full text | |||||
PMID: 39460624 IF: 16.6 | ||||||
161. | Schartel, L., Jann, C., Wierczeiko, A., Butto, T., Mündnich, S., Marchand, V., Motorin, Y., Helm, M., Gerber, S., Lemke, E.A., Selective RNA pseudouridinylation in situ by circular gRNAs in designer organelles, (2024), Nat Commun., Oct. 24, 15(1):9177, Full text | |||||
160. | Kristen, M., Lander, M., Kilz, L.-M., Gleue, L., Jörg, M., Bregeon, D., Hamdane, D., Marchand, V., Motorin, Y., Friedland, K., Helm, M.*, DORQ-seq: high-throughput quantification of femtomol tRNA pools by combination of cDNA hybridization and Deep sequencing, (2024), Nucleic Acid Res., Oct. 14, 52(18):e89, Full text | |||||
PMID: 339258547 IF: 16.6 | ||||||
159. | Gleue, L., Gräfen, B., Voigt, M., Schupp, M., Schneider, D., Fichter, M., Kuske, M., Mailänder, V., Tüttenberg, A.*, Helm, M.*, Dual Centrifugation-based Screening for pH-responsive Liposomes, (2024), ChemMedChem., Sep. 27, Online ahead of print, Full text | |||||
PMID: 39328087 IF: 3.5 | ||||||
158. | Ripp, A., Krämer, M., Barth, V., Moser, P., Haas, T.M., Singh, J., Huck, T., Gleue, L. Friedland, K., Helm, M.*, Jessen, H.J.*, The P(III)-amidite based synthesis of stable isotope labeled mRNA-cap-structures enables their sensitive quantitation from brain tissue, (2024), Angew Chem Int Ed Engl., Sep. 26, Online ahead of print, Full text | |||||
PMID: 39324525 IF: 16.6 | ||||||
157. | Toubdji, S., Thullier, Q., Kilz, L.-M., Marchand, V., Yuan, Y., Sudol, C., Goyenvalle, C., Jean-Jean, O., Rose, S., Douthwaite, S., Hardy, L., Baharoglu, Z., de Crecy-Lagard, V., Helm, M., Motorin, Y., Hamdane, D., Brégeon, D., Exploring a unique class of flavoenzymes: Identification and biochemical characterization of ribosomal RNA dihydrouridine synthase, (2024), Proc. Natl. Acad Sci U S A, Aug. 6, 121(32):e2401981121, Full text | |||||
PMID: 39078675 IF: 9.4 | ||||||
156. | Görlitz, K., Bessler, L., Helm, M., Schaffrath, R., Klassen, R., Fluoropyrimidines trigger decay of hypomodified tRNA in yeast, (2024), Nucleic Acid Res., May, 8, 52(10):5841-5851, Full text | |||||
PMID: 38716877 IF: 14.9 | ||||||
155. | Sudol, C., Kilz, L.-M., Marchand, V., Thullier, Q., Guérineau, V., Goyenvalle, C., Faivre, B., Toubdji, S., Lombard, M., Jean-Jean, O., de Crecy-Lagard, V., Helm, M., Motorin, Y., Brégeon, D., Hamdane, D., Functional redundancy in tRNA dihydrouridylation, (2024), Nucleic Acid Res., Apr. 29, 52(10):5880-5894, Full text | |||||
PMID: 38682613 IF: 14.9 | ||||||
154. | Bessler, L., Sirleaf, J., Kampf, C.J., Frankowska, K., Leszczyńska, G., Opatz, T., Helm, M.*, Esterification of Cyclic N6-threonylcarbamoyladenosine during RNA Sample Preparation, (2024), Chem Med Chem., Apr. 17, 19(13):e202400115, Full text | |||||
PMID: 38630955 IF: 3.5 | ||||||
153. | Bessler, L., Groß, J., Kampf, C.J., Opatz, T., Helm, M.*, Reversible oxidative dimerization of 4-thiouridines in tRNA isolates, (2024), RSC Chem Biol., Feb.1, 5(3):216-224, Full text | |||||
PMID: 38456039 IF: 4.1 | ||||||
152. | Jörg, M., Plehn, J.E., Kristen, M., Lander, M., Walz, L., Lietz, C., Wijns, J., Pichot, F., Rojas-Charry, L., Wirtz Martin, K.M., Ruffini, N., Kreim, N., Gerber, S., Motorin, Y., Endres, K., Rossmanith, W., Methner, A., Helm, M.*, Friedland, K.*, N1-methylation of adenosine (m1A) in ND5 mRNA leads to complex I dysfunction in Alzheimer's disease, (2024), Mol. Psychiatry, Jan. 29, 29(5):1427-1439, Full text | R25 | Delaunay, S., Helm, M., Frye, M, RNA modifications in physiology and disease: towards clinical applications, (2023), Nat Rev Genet., Sept. 15, Online ahead of print, Full text | |||
PMID: 38287100 IF: 11.0 | PMID: 37714958 IF: 59.9 | |||||
--2023-- | ||||||
-Originals- | -Reviews- | |||||
151. | Boulet. M., Gilbert, G., Renaud, Y., Schmidt-Dengler, M., Plantié, E., Bertrand, R., Nan, X., Jurkowski, T., Helm, M., Vandel, L., Waltzer, L., Adenine methylation is very scarce in the Drosophila genome and not erased by the ten-eleven translocation dioxygenase, (2023), Elife, Dec., 21:12:RP91655, Full text | |||||
PMID: 38126351 IF: 8.7 | ||||||
150. | Cirzi, C., Dyckow, J., Legrand, C., Schott, J., Guo, W., Perez Hernandez, D., Hisaoka, M., Parlato, R., Pitzer, C., van der Hoeven, F., Dittmar, G., Helm, M., Stoecklin, G., Schirmer, L., Lyko, F., Tuorto, F., Queuosine-tRNA promotes sex-dependent learning and memory formation by maintaining codon-biased translation elongation speed, (2023), EMBO J., Aug 23, 42(19):e112507, Full text | |||||
PMID: 37609797 IF: 11.4 | ||||||
149. | Wierczeiko, A., Pastore S., Mündnich, S., Busch, A.M., Dietrich, V., Helm, M., Butto, T., Gerber, S., NanopoReaTA: a user-friendly tool for nanopore-seq real-time transcriptional analysis, (2023), Bioinformatics, Aug 7, 39(8):btad492, Full text | |||||
PMID: 37549052 IF: 6.9 | ||||||
148. | García-Vílchez, R., Añazco-Guenkova, A.M., Dietman, S., López, J., Morón-Calvente, V., D'Ambrosi, S., Nombela, P., Zamacola, K., Mendizabal, I., García-Longarte, S., Zabala-Letona, A., Astobiza, I., Fernández, S., Paniagua, A., Miguel-López, B., Marchand, V., Alonso-López, D., Merkel, A., García-Tuñón, I., Ugalde-Olano, A., Loizaga-Iriarte, A., Lacas-Viscasilla, I., Unda, M., Azkargota, M., Elortza, F., Bárcena, L., Gonzalez-Lopez,M., Aransay, A.M., Di Domenico, T., Sánchez-Martín, M., De Las Rivas, J., Guil, S., Motorin, Y., Helm, M., Pandolfi, P.P., Carracedo, A., Blanco, S., METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer, (2023), Mol. Cancer, Jul 29, 22(1):119, Full text | |||||
PMID: 37516825 IF: 41.4 | ||||||
147. | Koch, J., Neuberger, M., Schmidt-Dengler, M., Xu, J., Carneiro, V. C., Ellinger, J., Kriegmair, M.C., Nuhn, P., Erben, P., Michel, M.S., Helm, M., Rodríguez-Paredes, M., Nientiedt, M., Lyko, F., Reinvestigating the clinical relevance of the m6A writer METTL3 in urothelial carcinoma of the bladder, (2023), iScience, Jul 11, 26(8):107300, Full text | |||||
PMID: 37554463 IF: 6.1 | ||||||
146. | Schwickert, M., Zimmermann, R. A., Habeck, T., Hoba, S. N., Nidoieva, Z., Fischer, T. R., Stark, M. M., Kersten, C., Lermyte, F., Helm, M.*, Schirmeister, T.*, Covalent S-Adenosylhomocysteine-Based DNA Methyltransferase 2 Inhibitors with a New Type of Aryl Warhead, (2023), ACS Med Chem Lett., May 9, 14(6):777-787, Full text | |||||
PMID: 37312859 IF: 4.6 | ||||||
145. | Bessler, L., Vogt, L. M., Lander, M., Dal Magro, C., Keller, P., Kühlborn, J., Kampf, C. J., Opatz, T., & Helm, M.*, A New Bacterial Adenosine-Derived Nucleoside as an Example of RNA Modification Damage, (2023), Angewandte Chemie (International ed. in English), Mar 6;62(11):e202217128, Full text | |||||
PMID: 36629490 IF:15.3 | ||||||
144. | Koshla, O., Vogt, L. M., Rydkin, O., Sehin, Y., Ostash, I., Helm, M., & Ostash, B. Landscape of Post-Transcriptional tRNA Modifications in Streptomyces albidoflavus J1074 as Portrayed by Mass Spectrometry and Genomic Data Mining, (2022), Journal of bacteriology, Epub 2022 Dec 5, J Bacteriol. 2023 Jan 26;205(1):e0029422 Full text | |||||
PMID: 36468867 IF: 3.5 | ||||||
--2022-- | ||||||
-Originals- | -Reviews- | |||||
143. | Pichot, F., Hogg, M. C., Marchand, V., Bourguignon, V., Jirström, E., Farrell, C., Gibriel, H. A., Prehn, J. H. M., Motorin, Y.*, & Helm, M.*, Quantification of substoichiometric modification reveals global tsRNA hypomodification, preferences for angiogenin-mediated tRNA cleavage, and idiosyncratic epitranscriptomes of human neuronal cell-lines, (2022), Computational and structural biotechnology journal, 21, Dec 19,21:401-417, Full text | R24 | Brégeon,D., Pecqueur, L., Toubdji, S., Sudol, C., Lombard, M., Fontecave, M., de Crécy-Lagard, V., Motorin, Y., Helm, M., Hamdane, D., Dihydrouridine in the Transcriptome: New Life for This Ancient RNA Chemical Modification, (2022), ACS Chem Biol., Jun. 23, Full text | |||
PMID: 36618980 IF:7.3 | PMID: 35737906 IF:4.4 | |||||
142. | Zimmermann, R. A., Schwickert, M., Meidner, J. L., Nidoieva, Z., Helm, M.*, & Schirmeister, T.*, An Optimized Microscale Thermophoresis Method for High-Throughput Screening of DNA Methyltransferase 2 Ligands, (2022), ACS pharmacology & translational science, Oct. 19., 5(11):1079-1085 | R23 | Helm, M., Motorin, Y., Phosphorylation found inside RNA, (2022), Nature, May, 605(7909):234-235, Full text | |||
PMID: 36407957 IF: 4.9 | PMID: 35478019 IF: 42.8 | |||||
141. | Bessler, L.#, Kaur, N.#, Vogt, L.-M.#, Flemmich, L., Siebenaller, C., Winz, M.-L., Tuorto, F., Micura, R., Ehrenhofer-Murray, A.E.*, Helm, M.*, Functional integration of a semi-synthetic azido-queuosine derivative into translation and a tRNA modification circuit, (2022), Nucleic Acids Res., Sep. 28, 50(18):10785-10800, Full text | R22 | Fischer TR, Meidner L, Schwickert M, Weber M, Zimmermann RA, Kersten C, Schirmeister T, Helm M., Chemical biology and medicinal chemistry of RNA methyltransferases, (2022), Nucleic Acid Res., Apr. 22, 50(8):4216-4245, Full text | |||
PMID: 36169220 IF: 19.2 | PMID: 35412633 IF: 19.2 | |||||
140. | Ravichandran, M., Rafalski, D., Davies, C.I., Ortega-Recalde, O., Nan, X., Glanfield, C.R., Kotter, A., Misztal, K., Wang, A.H., Wojciechowski, M., Rażew, M., Mayyas, I.M., Kardailsky, O., Schwartz, U., Zembrzycki, K., Morison, I.M., Helm, M., Weichehan, D., Jurkowska, Krueger, F., Plass, C., Zacharias, M., Bochtler, M., Hore, T.A., Jurkowski, T.P., Pronounced sequence specificity of the TET enzyme catalytic domain guides its cellular function, (2022), Sci Adv., Sep. 9, 8(36):eabm2427, Full text | |||||
PMID: 36070377 IF: 14.1 | ||||||
139. | Hertler, J.#, Slama, K.#, Schober, B., Özrendeci, Z., Marchand, V., Motorin, Y., Helm, M.*, T.P., Synthesis of point-modified mRNA., (2022), Nucleic Acid Res., Sep. 5, 50(20):e115, Full text | |||||
PMID: 36062567 IF: 19.2 | ||||||
138. | Henry, B.A., Marchand, V., Schlegel, B.T., Helm, M., Motorin, Y., Lee, N., Pseudouridylation of Epstein-Barr Virus Noncoding RNA EBER2 Facilitates Lytic Replication, (2022), RNA, Sep. 13, 28(11):1542-1552, Full text | |||||
PMID: 36100352 IF: 4.9 | ||||||
137. | Cavallin, I., Bartosovic, M., Skalicky, T., Rengaraj, P., Demko, M., Schmidt-Dengler, M.C., Drino, A., Helm, M., Vanacova, S., HITS-CLIP analysis of human ALKBH8 reveals interactions with fully processed substrate tRNAs and with specific noncoding RNAs, (2022), RNA, Oct. 3, 28(12):1568-1581, Full text | |||||
PMID: 36192131 IF: 4.9 | ||||||
136. | Kallert, E., Fischer, T.R., Schneider, S., Grimm, M., Helm, M., Kersten, C., Protein-Based Virtual Screening Tools Applied for RNA-Ligand Docking Identify New Binders of the preQ1-Riboswitch, (2022), J Chem. Inf. Model, Sep. 12, 62(17):4134-4148, Full text | |||||
PMID: 35994617 IF: 6.2 | ||||||
135. | Schwickert, M., Fischer, T.R., Zimmermann, R.A., Hoba, S.N., Meidner, J.L., Weber, M., Weber, M., Stark, M.M., Koch, J., Jung, N., Kersten, C., Windbergs, M., Lyko, F., Helm, M.*, Schirmeister, T.*, Discovery of Inhibitors of DNA Methyltransferase 2, an Epitranscriptomic Modulator and Potential Target for Cancer Treatment, (2022), J Med Chem., Jul. 18, 65(14):9750-9788, Full text | |||||
PMID: 35849534 IF: 6.3 | ||||||
134. | Pichot, F., Marchand V., Helm, M., Motorin Y., Machine learning algorithm for precise prediction of 2'-O-methylation (Nm) sites from experimental RiboMethSeq datasets, (2022), Methods., Jul, 203:311-321, Full text | |||||
PMID: 35314341 IF: 4.7 | ||||||
133. | Richter, F.#, Plehn. J.E.#, Bessler, L., Hertler, J., Jörg, M., Cirzi, C., Tuorto, F., Friedland, K.*, Helm, M.*, RNA marker modifications reveal the necessity for rigorous preparation protocols to avoid artifacts in epitranscriptomic analysis, (2022), Nucleic Acid Res., May 6, 50(8):4201-4215, Full text | |||||
PMID: 34850949 IF: 19.2 | ||||||
132. | Barthels, F., Hammerschmidt, S.J., Fischer, T.R., Zimmer, C., Kallert, E., Helm, M., Kersten, C., Schirmeister, T., A low-cost 3D-printable differential scanning fluorometer for protein and RNA melting experiments, (2022), HardwareX, Apr., Full text | |||||
DOI: https://doi.org/10.1016/j.ohx.2022.e00256 | ||||||
131. | Biedenbänder, T., de Jesus, V., Schmidt-Dengler, M., Helm, M., Corzilius, B., Fürtig, B., RNA modifications stabilize the tertiary structure of tRNAfMet by locally increasing conformational dynamics, (2022), Nucleic Acid Res., Feb. 28, 50(4):2334-2349, Full text | |||||
PMID: 35137185 IF: 16,5 | ||||||
--2021-- | ||||||
-Originals- | -Reviews- | |||||
130. | Schöller, E., Marks, J., Marchand, V., Bruckmann, A., Powell, C.A., Reichold, M., Mutti, C.D., Dettmer, K., Feederle, R., Hüttelmaier, S., Helm, M., Oefner, P., Minczuk, M., Motorin, Y., Hafner, M., Meister, G., Balancing of mitochondrial translation trough METTL8-mediated m3 C modification of mitochondrial tRNAs, (2021), Mol Cell., Nov. 12, 81(23:4810-4825, Full text | R21 | Motorin, Y., Helm, M., RNA nucleotide methylation: 2021 update, (2021), Wiley Interdiscip Rev RNA, Dec. 15, e1691, Full text | |||
PMID: 34774131 IF: 17,9 | PMID: 34913259 IF: 11,9 | |||||
129. | Fradejas-Villar, N., Bohleber, S., Zhao, W., Reuter, U., Kotter, A., Helm, M., Knoll, R., McFarland, R., Taylor, R.W., Mo, Y., Miyauchi, K., Sakaguchi, Y., Suzuki, T., Schweizer, U., The Effect of tRNA [Ser]Sec Isopentenylation on Selenoprotein Expression, (2021), Molecular Sciences, Oct. 23, 22(21) 11454, Full text | R20 | Fagan, S.G., Helm, M., Prehn, J.H.M., tRNA-derived fragments: A new class of non-coding RNA with key roles in nervous system function and dysfunction, (2021), Prog. Neurobiol., Oct., 205:102118, Full text | |||
PMID: 34768885 IF: 5,9 | PMID: 34245849 IF: 11,6 | |||||
128. | Johann, K., Bohn, T., Shahneh, F., Luther, N., Birke, A., Jaurich, H., Helm, M., Klein, M., Raker, V.K., Bopp, T., Barz, M., Becker, C., Therapeutic melanoma inhibition by local micelle-mediated cyclic nucleotide repression, (2021), Nat. Commun., Oct. 13, 12(1):5981, Full text | R19 | Helm, M., Schmidt-Dengler, M.C., Weber, M., Motorin, Y., General Principles for the Detection of Modified Nucleotides in RNA by Specific Reagents, (2021), Adv. Biol. (Weinh), Sep. 17, 5(10):e2100866 | |||
PMID:34645812 IF: 12,1 | PMID: 34535986 IF: 3,5 | |||||
127. | Schmidt, J., Goergens, J., Pochechueva, T., Kotter, A., Schwenzer, N., Sitte, M., Wener, G., Altmüller, J., Thiele, H., Nürnberg, P., Isensee, J., Li, Y., Müller, C., Leube, B., Reinhardt, H.C., Hucho, T., Salinas, G., Helm, M., Jachimowicz, R.D., Wieczorek, D., Kohl, T., Lehnhart, S. E., Yigit, G., Wollnik, B., Biallelic variants in YRDC cause a developmental disorder with progeroid features, (2021), Hum Genet., Sep. 20, 140(12):1679-1693, Full text | |||||
PMID: 34545459 IF: 5,7 | ||||||
126. | Bawankar, P., Lence, T., Paolantoni, C., Haussmann, I.U., Kazlauskiene, M., Jacob, D., Heidelberger, J.B., Richter, F.M., Nallasivan, M.P., Morin, V., Kreim, N., Beli, P., Helm, M., Jinek, M., Soller, M., Roignant, J.-Y., Hakai is required for stabilization of core components of the m6A mRNA methylation machinery, (2021), Nat Commun., Jun. 18, 12(1):3778, Full text | |||||
PMID: 34145251 IF: 12,1 | ||||||
125. | Siebenaller, C., Schlösser, L., Junglas, B., Schmidt-Dengler, M., Jacob, D., Hellmann, N., Sachse, C., Helm, M., Schneider, D., Binding and/or hydrolysis of purine-based nucleotides is not required for IM30 ring information, (2021), FEBS Lett., Jun. 1, 595(14):1876-1885, Full text | |||||
PMID: 34060653 IF: 3,1 | ||||||
124. | Duda, K.J., Ching, W.R., Jerabek, L., Shukeir, N., Erikson, G., Engist, B., Onishi-Seebacher, M., Perrera, V., Richter, F., Mittler, G., Fritz, K., Helm, M., Knuckles, P., Bühler, M., Jenuwein, T., m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA: DNA hybrid formation in mouse heterochromatin, (2021), Nucleic Acid Res., May 17, 49(10):5568-5587, Full text | |||||
PMID: 33999208 IF: 11,6 | ||||||
123. | Coll-SanMartin, L., Davalos, V., Piñeyro, D., Rosselló-Tortella, M., Bueno-Costa, A., Setien, F., Villanueva, A., Granada, I., Ruiz-Xiviller, N., Kotter, A., Helm, M., Yokota, J., Kawabata-Iwakawa, R., Kohno, T., Esteller, M., Gene Amplification-Associated Overexpression of the Selenoprotein tRNA Enzyme TRIT1 Confers Sensivitiy to Arsenic Trioxide in Small-Cell Lung Cancer, (2021), Cancers, Apr. 14, 13(8):1869, Full text | |||||
PMID: 33919717 IF: 6,1 | ||||||
122. | Cunha Navarro, I., Tuorto, F., Jordan, D., Legrand, C., Price, J., Braukmann, F., Hendrik, A.G. Akay, A., Kotter, A., Helm, M., Lyko, F., Miska, E.A., Translational adaptation to heat stress is mediated by RNA 5-methylcytosine in Caenorhabditis elegans, (2021), EMBO J., Mar. 15, e105496, Full text | |||||
PMID: 33283887 IF: 9,9 | ||||||
121. | Werner, S., Galliot, A., Pichot, F., Kemmer, T., Marchand, V., Sednev, M.V., Lence, T., Roignant, J.-Y., König, J., Höbartner, C., Motorin, Y., Hildebrandt, A., Helm, M.*, NOseq: amplicon sequencing evaluation method for RNA m6A sites after chemical deamination, (2021), Nucleic Acids Res., Feb. 26, 49(4):e23, Full text | |||||
PMID: 33313868 IF: 11,5 | ||||||
120. | Schupp, J., Christians, A., Zimmer, N., Gleue, L., Jonuleit, H., Helm, M., Tuettenberg, A., In-Depth Immune-Onclogy Studies of the Tumor Microenvironment in a Humanized Melanoma Mouse Model, (2021), Int J Mol Sci., Jan. 20, 22(3):1011, Full text | |||||
PMID: 33498319 IF: 4,6 | ||||||
119. | Pichot, F., Marchand, V., Helm, M., Motorin, Y., Non-Redundant tRNA References Sequences for Deep Sequencing Analysis of tRNA Abundance and Epitranscriptomic RNA Modifications, (2021), Genes, Jan. 10, 12(1):81, Full text | |||||
PMID: 33435213 IF: 3,6 | ||||||
--2020-- | ||||||
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118. | Galvanin, A., Vogt, L.-M., Grober, A., Freund, I., Ayadi, L., Bourguignon-Igel, V., Bessler, L., Jacob, D., Eigenbrod, T., Marchand, V., Dalpke, A., Helm, M., Motorin, Y., Bacterial tRNA 2'-O-metyhlation is dynamically regulated under stress conditions and modulates innate immune response, (2020), Nucleic Acids Res., Dec. 16, 48(22):12833-12844, Full text | R18 | Ruggieri, A., Helm, M., Chatel-Chaix, L., An epigenetic "extreme makeover": the methylation of flaviviral RNA (and beyond), (2020), RNA Biol., Dec. 23, Online ahead of print, Full text | |||
PMID: 33275131 IF: 11,5 | PMID: 33356825 IF: 5,4 | |||||
117. | Gleue, L., Schupp, J., Zimmer, N., Becker, E., Frey, H., Tuettenberg, A.*, Helm, M.*, Stability of Alkyl Chain-Mediated Lipid Anchoring in Liposomal Membranes, (2020), Cells., Sep. 29, 9(10):2213, Full text | |||||
PMID: 33003620 IF: 4,4 | ||||||
116. | Marchand, V., Pichot, F., Neybecker, P., Ayadi, L., Bourguignon-Igel, V., Wacheul, L., Lafontaine, D.L.J., Pinzano, A., Helm, M., Motorin, Y., HydraPsiSeq: a method for systematic and quantitative mapping of pseudouridines in RNA, (2020), Nucleic Acid Res., Sep. 25, 48(19):e10, Full text | |||||
PMID: 32976574 IF: 11.5 | ||||||
115. | Kristen, M., Plehn, J., Marchand, V., Friedland, K., Motorin, Y., Helm, M., Werner, S.*, Manganese Ions Individually Alter the Reverse Transcription Signature of Modified Ribonucleosides., (2020), Genes (Basel), Aug. 18, 11(8):950, Full text | |||||
PMID: 32824672 IF: 3.8 | ||||||
114. | Weichmann, F., Hett, R., Schepers, A., Ito-Kureha, T., Flatley, A., Slama, K., Hastert, F., Angstmann, N., Cardoso, C.M., König, J., Huettelmaier, S., Dieterich, C., Canzar, S. Helm, M., Heissmeyer, V., Feederle, R., Meister, G., Validation strategies for antibodies targeting modified ribonucleotides., (2020), RNA, Jul. 7, 26(10):1489-1506, Full text | |||||
PMID: 32636310 IF: 5.5 | ||||||
113. | Vilardo, E., Amman, F., Toth, U., Kotter, A., Helm, M., Rossmanith, W., Functional Characterization of the Human tRNA Methyltransferases TRMT10A and TRMT10B., (2020), Nucleic Acids Res., Jun. 19, 48(11):6157-6169, Full text | |||||
PMID: 32392304 IF: 11,5 | ||||||
112. | Henry, B.A., Kanarek, J.P., Kotter, A., Helm, M., Lee, N., 5-Methylcytosine Modification of an Epstein-Barr Virus Decreases its Stability., (2020), RNA, Apr. 30, 26(8):1038-1048, Full text | |||||
PMID: 32354721 IF: 5,5 | ||||||
111. | Werner, S.#, Schmidt, L.#, Marchand, V., Kemmer, T., Falschlunger, C., Sednev, M.V., Bec, G., Ennifar, E., Höbartner, C., Micura, R., Motorin, Y., Hildebrandt A.*, Helm, M.*, Machine Learning of reverse transcription signatures of variegated polymerases allows mapping and discrimination of methylated purines in limited transcriptomes, (2020), Nucleic Acids Res., Feb. 25, 48(7):3734-3746, Full text | |||||
PMID: 32095818 IF: 11,2 | ||||||
110. | Meyer, B., Immer, C., Kaiser, S., Sharma, S., Yang, J., Watzinger, P., Weiß, L., Kotter, A., Helm, M., Seitz, H.M., Kötter, P., Kellner, S., Entian, K.D., Wöhnert, J., Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs., (2020), Nucleic Acids Res., Febr. 20, 48(3):1435-1450, Full text | |||||
PMID: 31863583 IF: 11,2 | ||||||
109. | Pichot, F., Marchand, V., Ayadi, L., Bourguignon-Igel, V., Helm, M., Motorin, Y., Holistic Optimization of Bioinformatic Analysis Pipeline for Detection and Quantification of 2'-O-Methylations in RNA by RiboMethSeq., (2020), Front Genet., Febr. 13, 11:38, Full text | |||||
PMID: 32117451 IF: 3,8 | ||||||
--2019-- | ||||||
-Originals- | -Reviews- | |||||
108. | Tabujew, I., Heidari, M., Freidel, C., Helm, M., Tebbe, L., Wolfrum, U., Nagel-Wolfrum, K., Koynov, K., Biehl, P., Schacher, F.H., Potestio, R., Peneva, K., Tackling the Limitations of Copolymeric Small Interfering RNA Delivery Agents by a Combined Experimenta-Computational Approach, (2019), Biomacromolecules, Nov. 4,20(12):4389-4406, Full text | R17 | Helm, M., Lyko, F., Motorin, Y., Limited antibody specificity compromises epitranscriptomic analyses, (2019), Nat. Commun., Dec. 11, 10(1):5669, Full text | |||
PMID: 31686497 IF: 5,7 | PMID: 31827101 IF: 12,4 | |||||
107. | Pannwitt, S., Slama, K., Depoix, F., Helm, M., Schneider, D., Against Expectations: Unassisted RNA Adsorption onto Negatively Charged Lipid Bilayers., (2019), Langmuir, Oct. 31, 35(45):14704-14711, Full text | R16 | Freund, I., Eigenbrod, T., Helm, M., Dalpke, A.H., RNA Modifications Modulate Activation of Innate Toll-Like Receptors., (2019), Genes (Basel), Jan. 29, 10(2), Full text | |||
PMID: 31626734 IF: 3,7 | PMID: 30699960 IF: 3,2 | |||||
106. | Tabujew, I., Willig, M., Leber, N., Freidel, C., Negwer, I., Koynov, K., Helm, M., Landfester, K., Zentel, R., Peneva, K., Mailänder, V., Overcoming the barrier of CD8+T cells: Two types of nano-sized carriers for siRNA transport., (2019), Acta Biomater., Oct. 04, 35(45):14704-14711, Full text | R15 | Motorin, Y., Helm, M., Methods for RNA Modification Mapping Using Deep Sequencing: Established and New Emerging Technologies, (2019), Genes (Basel), Jan. 9,10(1), Full text | |||
PMID: 31586726 IF: 6,4 | PMID: 30634534 IF: 3,2 | |||||
105. | Schmidt, L.#, Werner, S.#, Kemmer, T., Niebler, S., Kristen, M., Ayadi, L., Johe, P., Marachand, V., Schirmeister, T., Motorin, Y., Hildebrandt, A.*, Schmidt, B,*. Helm, M.*, Graphical Workflow System for Modification Calling by Machine Learning of Reverse Transcription Signatures., (2019), Front Genet., Sep. 25, 10:876, Full text | |||||
PMID: 31608115 IF: 4,2 | ||||||
104. | Weber, C., Voigt, M., Simon, J., Danner, A.K., Frey, H., Mailänder, V., Helm, M., Morsbach, S., Landfester, K., Functionalization of Liposomes with Hydrophilic Polymers Results in Macrophage Uptake Independent of the Protein Corona., (2019), Biomacromolecules., Aug. 12, 20(8):2989-2999, Full text | |||||
PMID: 31268685 IF: 5,7 | ||||||
103. | Carter, J.M., Emmett, W., Mozos, I.R., Kotter, A., Helm, M., Ule, J., Hussain, S., 'FICC-Seq: a method for enzyme-specified profiling of methyl-5-uridine in cellular RNA, (2019), Nucleic Acid Res., Jul. 30, 47(19):e113, Full text | |||||
PMID: 31361898 IF: 10,2 | ||||||
102. | Kaiser, R. W. J., Ignarski, M., Van Nostrand, E. L., Frese, C.K., Jain, M., Cukoski, S., Heinen, H., Schaechter, M., Seufert, L., Bunte, K., Frommolt, P., Keller, P., Helm, M., Bohl, K., Höhne, M., Schermer, B., Benzing, T., Höpker, K., Dieterich, C., Yeo, G. W., Müller, R. U., Fabretti, F., A protein-RNA interaction atlas of the ribosome biogenesis factor AATF, (2019), Sci. Rep., Jul. 30, 9(1):11071, Full text | |||||
PMID: 31363146 IF: 4,1 | ||||||
101. | Freund, I., Buhl, D.K., Boutin, S., Kotter, A., Pichot, F., Marchand, V., Vierbuchen, T., Heine, H., Motorin, Y., Helm, M., Dalpke, A.H., Eigenbrod, T., 2'-O-methylation within prokaryotic and eukaryotic tRNA inhibits innate immune activation by endosomal Toll-like receptors but does not affect recognition of whole organisms, (2019), RNA., Apr. 24, 25(7):869-880, Full text | |||||
PMID: 31019095 IF: 3,6 | ||||||
100. | Krutyholowa, R., Hammermeister, A., Zabel, R., Abdel-Fattah, W., Reinhardt-Tews, A., Helm, M., Stark, M.J.R., Breunig, K.D., Schaffrath, R., Glatt, S.,Kti12, a PSTK-like tRNA dependent A TPase essential for tRNA modification by Elongator, (2019), Nucleic Acids Rs., Mar. 27, 4814–4830, Full text | |||||
PMID: 30916349 IF: 10,6 | ||||||
99. | Jacob, D., Thüring, K., Galliot, A., Marchand, V., Galvanin, A., Ciftci, A., Scharmann, K., Stock, M., Roignant, J.Y., Leidel, S.A., Motorin, Y., Schaffrath,R., Klassen, R., Helm, M., Absolute quantification of noncoding RNA by microscale thermophoresis, (2019), Angew. Chem. Int. Ed. Engl., Mar. 20, 58(28):9565-9569, Full text | |||||
PMID: 30892798 IF: 12,1 | ||||||
98. | Neukranz, Y., Kotter, A., Beilschmidt, L., Marelja, Z., Helm, M., Gräf, R., Leimkühler, S., Analysis of the cellular roles of MOCS3 identifies a MOCS3-independent localization of NFS1 at the tips of the centrosome., (2019), Biochemistry, Feb. 28, 58(13):1786-1798, Full text | |||||
PMID: 30817134 IF: 3,0 | ||||||
97. | Fricker, R., Brogli, R., Luidalepp, H., Wyss, L., Fasnacht, M., Joss, O., Zywicki, M., Helm, M., Schneider, A., Cristodero, M., Polacek, N., A tRNA half modulates translation as stress response in Trypanosoma, (2019), Nature communications, Jan. 10, 10(1):118, Full text | |||||
PMID: 30631057 IF: 12,4 | ||||||
--2018-- | ||||||
-Originals- | -Reviews- | |||||
96. | Marchand, V., Ayadi, L., Ernst, F.G.M, Hertler, J., Bourguignon-Igel.V., Galvanin, A., Kotter, A., Helm, M., Lafontaine, D.L.J., Motorin, Y., AlkAniline-Seq: Profiling of m7 G and m3 C RNA Modifications at Single Nucleotide Resolution., (2018), Angew. Chem. Int. Ed. Engl., Dec. 17, 57(51):16785-16790, Full text |
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PMID: 30370969 IF: 12,2 | ||||||
95. | Negwer, I., Best, A., Schinnerer, M., Schäfer, O., Capeloa, L., Wagner, M., Schmidt, M., Mailänder, V., Helm, M., Barz, M., Butt, H.J., Koynov, K., Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy, (2018), Nat. Commun., Dec. 13, 9(1):5306, Full text | |||||
PMID: 30546066 IF: 12,4 | ||||||
94. | Keller, P., Freund, I., Marchand, V., Bec, G., Huang, R., Motorin, Y., Eigenbrod, T., Dalpke, A., Helm, M., Double methylation of tRNA-U54 to 2'-O-methylthymidine (TM) synergistically decreases immune response by Toll-like receptor 7., (2018), Nucleic Acids Res., Aug. 8, 9764–9775, Full text |
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PMID: 30102387 IF: 11,6 | ||||||
93. | Dal Magro, C., Keller, P., Kotter, A., Werner, S., Duarte, V., Marchand, V., Ignarski, M., Freiwald, A., Müller, R.U., Dietrich, C., Motorin, Y., Butter, F., Atta, M., Helm, M., A vastly increased chemical variety of RNA modifications that includes a thioacetal structure, (2018), Angew. Chem. Int. Ed. Engl., Apr. 6, 57(26):7893-7897, Full text |
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PMID: 29624844 IF: 12 | ||||||
92. | Knuckles, P., Lence, T., Haussmann, I. U., Jacob, D., Kreim, N., Carl, S.H., Masiello, I., Hares, T., Villaseñor, R., Hess, D., Andrade-Navarro, M.A., Biggiogera, M., Helm, M., Soller, M., Bühler, M., Roignant, J.Y., Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d., (2018), Genes Dev., Mar. 13, 32(5-6):415-429, Full text |
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PMID: 29535189 IF: 9,4 | ||||||
91. | Aschenbrenner, J., Werner, S., Marchand, V., Adam, M., Motorin , Y., Helm, M., Marx, A., Engineering of a DNA polymerase for direct m6A Sequencing, (2018), Angew. Chem. Int. Ed. Engl., Jan. 8, 57,417-421. Full Text | |||||
PMID: 29115744 IF: 12 | ||||||
--2017-- | ||||||
-Originals- | -Reviews- | |||||
90. | Boccaletto, P., Machnicka, M.A., Purta, E., Piatkowski, P., Baginski, B., Wirecki, T.K., de Crécy-Lagard, V., Ross, R., Limbach, P.A., Kotter, A., Helm, M., Bujnicki, J.M., MODOMICS: a database of RNA modification Pathways. 2017 update., (2017), Nucleic Acid Research., Nov. 2, 46(D1):D303-D307, Full Text | R14 | Helm, M., Motorin, Y.,Detecting RNA modifications in the epitranscriptome: predict and validate, (2017), Nature Reviews Genetics, Feb. 20, Full text | |||
PMID: 29106616 IF: 10,2 | PMID: 28216634 IF: 41,5 | |||||
89. | Negwer, I., Hirsch, M., Kaloyanova, S., Brown, T., Peneva, K., Butt, H.J., Koynov, K., Helm, M., Modulation of Mitochondriotropic Properties of Cyanine Dyes by in Organello Copper-Free Click Reaction., (2017), Chembiochem., Sep. 19, 18(18):1814-1818, Full Text | |||||
PMID: 28704573 IF: 2,8 | ||||||
88. | Weber, B., Kappel, C., Scherer, M., Helm, M., Bros. M., Grabbe, S., Barz, M., PeptoSomes for Vaccination: Combining Antigen and Adjuvant in Polypept(o)ide-Based Polymersomes., (2017), Macromol Biosci., Jul. 31, 17(10), Full Text | |||||
PMID: 28759159 IF: 3,3 | ||||||
87. | Legrand, C., Tuorto, F., Hartmann, M., Liebers, R., Jacob, D., Helm, M., Lyko, F., Statistically robust methylation calling for whole-transcriptome bisulfite sequencing reveals distinct methylation patterns for mouse RNAs, (2017), Genome Res., Jul. 6, 27(9):1589-1596, Full text | |||||
PMID: 28684555 IF: 11,9 | ||||||
86. | Schmitt, F.C.F., Freund, I., Weigand, M.A., Helm, M., Dalpke, A.H., Eigenbrod, T., Identification of an optimized 2'-O-methylated tri-nucleotide RNA motif inhibiting Toll-like receptor 7 and 8, (2017), RNA, Jun. 2, 23(9):1344-1351, Full text | |||||
PMID: 28576825 IF: 4,6 | ||||||
85. | Hellmuth, I., Freund, I., Schlöder, J., Seidu-Larry, S., Thüring, K., Slama, K., Langhanki, J., Kaloyanova, S., Eigenbrod, T., Krumb, M., Röhm, S., Peneva K., Opatz, T., Jonuleit, H., Dalpke, A.H., Helm, M., Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor, (2017), 7. Fronti. Immunol., Mar. 24, 8:312, Full text | |||||
DOI: 10.3389/fimmu.2017.00312 IF:5,7 | ||||||
84. | Schmid, K., Adobes-Vidal, M., Helm, M., Alkyne-Functionalized Coumarin Compound for Analytic and Preparative 4-Thiouridine Labeling, (2017), Bioconjugate Chemistry, Mar. 15, 28(4):1123-1134, Full text | |||||
PMID: 28263563 IF:4,5 | ||||||
83. | Marchand, V., Pichot, F., Thüring, K., Avadi, L., Freund, I., Dalpke, A., Helm, M., Motorin, Y., Next-Generation Sequencing-Based RiboMethSeq Protocol for Analysis of tRNA 2'-O-Methylation, (2017), Biomolecules, Feb. 9, 7(1), Full Text | |||||
PMID: 28208788 IF: 5,8 | ||||||
--2016-- | ||||||
-Originals- | -Reviews- | |||||
82. | Lence, T., Akhtar, J., Bayer, M., Schmid, K., Spindler, K., Ho, CH., Kreim, N., Andrade-Navarro, MA., Poeck, B., Helm, M., Roignant, JY., m6A modulates neuronal functions and sex determination in Drosophila, (2016), Nature, Dec. 8, 540(7632):242-247, Full text | R13 | Motorin, Y., Seidu-Larry, S., Helm, M., (2016) DNA and RNA Pyrimidine Nucleobase Alkylation at the Carbon-5 Position. Adv Exp Med Biol., 945:19-33. Full text | |||
PMID: 27919077 IF: 38,2 | PMID: 27826833 IF: 1,9 | |||||
81. | Kaiser, S., Jurkowski, TP., Kellner, S., Schneider, D., Jeltsch, A., Helm, M., The RNA methyltransferase Dnmt2 methylates DNA in the structural context of a tRNA, (2016)RNA Biology, Nov., 7:1-11, Full text | R12 | Jeltsch, A., Ehrenhofer-Murray, A., Jurkowski, TP., Lyko, F., Reuter, G., Ankri, S., Nellen, W., Schaefer, M., Helm, M. Mechanism and biological role of Dnmt2 in Nucleic Acid Methylation, (2016) RNA Biology., Sep. 2, 14(9):1108-1123, Full Text | |||
PMID: 27819523 IF: 4,1 | PMID: 27232191 IF: 5,2 | |||||
80. | Hauenschild, R., Werner, S., Tserovski, L., Hildebrandt, A., Motorin, Y., Helm, M., CoverageAnalyzer (CAn): A Tool for Inspection of Modification Signatures in RNA Sequencing Profiles, (2016)Biomolecues., Nov. 10, 6(4), Full text | |||||
PMID: 27834909 IF: 5,8 | ||||||
79. | Falckenhayn, C., Carneiro, VC., de Mendonça Amarante, A., Schmid, K., Hanna, K., Kang, S., Helm, M., Dimopoulos, G., Fantappié, MR., Lyko, F., Comprehensive DNA methylation analysis of the Aedes aegypti genome, (2016) Sci. Rep., Nov. 2, 6:36444, Full text | |||||
PMID: 27805064 IF: 5,2 | ||||||
78. | Jüdes, A., Bruch, A., Klassen, R., Helm, M., Schaffrath, R., Sulfur transfer and activation by ubiquitin-like modifier system Uba4Urm1 link protein urmylation and tRNA thiolation in yeast, (2016), Microb Cell., Oct. 24, 3(11):554-564, Full text | |||||
PMID: 28357324 IF: N/A | ||||||
77. | Müller, S., Fritz, T., Gimnich, M., Worm, M., Helm, M., Frey, H., Biodegradable Hyperbranched Polyether-Lipids with In-Chain pH-Sensitive Linkages, (2016) Polym. Chem., Sep. 19, Full text | |||||
DOI: 10.1039/C6PY01308B IF:5,7 | ||||||
76. | Tserovski, L., Helm, M.,Diastereoselectivity of 5-methyluridine osmylation is inverted inside an RNA chain., (2016)Bioconjugate Chemistry, Aug. 19, 27(9):2188-97, Full text | |||||
PMID: 27540864 IF:4,5 | ||||||
75. | Fritz, T., Voigt, M., Worm, M., Negwer, I., Müller, SS., Kettenbach, K., Ross, TL., Roesch, F., Koynov, K., Frey, H., Helm, M., Orthogonal Click Conjugation to the Liposomal Surface Reveals the Stability of the Lipid Anchorage as Crucial for Targeting., (2016)Chemistry, Aug. 8, 22(33):11578-82 | |||||
PMID: 27403892 IF:5,8 | ||||||
74. | Nick, TA., de Oliverira, TE., Pilat, DW., Spenkuch, F., Butt, HJ., Helm, M., Netz, PA., Berger, R., Stability of a Split Streptomycin Binding Aptamer., (2016)The Journal of physical chemistry. B., Jul. 14, 120(27):6479-89 , Full text | |||||
PMID: 27281393 IF:3,2 | ||||||
73. | Marchand, V., Blanloeil- Oillo, F., Helm, M., Motorin, Y., Illumina-based RiboMethSeq approach for mapping of 2'-O-Me residues in RNA., (2016), Nucleic Acid Research, Jun. 14, 44(16):e135, Full text | |||||
PMID: 27302133 IF:9,1 | ||||||
--2015-- | ||||||
-Originals- | -Reviews- | |||||
72. | Kienhöfer, S., Musheev, MU., Stapf, U., Helm, M., Schomacher, L., Niehrs, C., Schäfer, A., (2015) GADD45a physically and functionally interacts with TET1. Differentiation, Nov. 03, 90(1-3):59-68, Full text | |||||
PMID: 26546041 IF:3,4 | ||||||
71. | Vogt, G., Falckenhayn, C., Schrimpf, A., Schmid, K., Hanna, K., Pantelein, J., Helm, M., Schulz, R., Lyko, F., (2015) The marbled crayfish as a paradigm for saltational speciation by autopolyploidy and parthenogenesis in animals. Biology Open, Oct. 30, 4(11):1583-94, Full Text | |||||
PMID: 26519519 IF:2,4 | ||||||
70. | Müller, M., Hartmann, M., Schuster, I., Bender, S., Thüring, KL., Helm, M., Katze, JR., Nellen, W., Lyko, F., Ehrenhofer-Murray, AE. (2015) Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine, Nucleic Acids Research, Sep. 30, 43(22):10952-62, Fulltext | |||||
PMID: 26424849 IF:9,1 | ||||||
69. | Hauenschild, R., Tserovski, L., Schmid, K., Thüring, K., Winz, ML., Sharma, S., Entian, KD., Wacheul, L., Lafontaine, DL., Anderson, J., Alfonzo, J., Hildebrandt, A., Jäschke, A., Motorin, Y., Helm, M., (2015) The reverse transcription signature of N-1-methyladenosine in RNA-Seq is sequence dependent, Nucleic Acids Research, Sep. 13, 43(20):9950-64, Fulltext | |||||
PMID: 26365242 IF:9,1 | ||||||
68. | Schmid, K., Thüring, K., Keller, P., Ochel, A., Kellner, S., Helm, M., (2015) Variable presence of 5-methylcytosine in commercial RNA and DNA, RNA Biology, Aug. 14, 12(10):1152-8, Full text | |||||
PMID: 26274337 IF:5,0 | ||||||
67. | Bourgeois, G., Ney, M., Gaspar, I., Aiqueperse, C., Schaefer, M., Kellner, S., Helm, M., Motorin, Y. (2015) Eukaryotic rRNA Modification by Yeast 5-Methylcytosine-Methyltransferases and Human Proliferation-Associated Antigen p120, PLoS One, Jul. 21, 10(7):e0133321, Full text | |||||
PMID: 26196125 IF:3,2 | ||||||
66. | Shanmugam, R., Fierer, J., Kaiser, S., Helm, M., Jurkowski, T. P., Jeltsch, A. (2015) Cytosine methylation of tRNA-Asp by DNMT2 has a role in translation of proteins containing poly-Asp sequences, CellDiscovery, Jun. 9, 1, 15010, Fulltext | |||||
doi:10.1038/celldisc.2015.10 IF:N/A | ||||||
65. | Domingo,O., Hellmuth, I., Jaeschke, A., Kreutz, C., Helm, M. (2015) Intermolecular 'cross-torque': the N4-cytosine propargyl residue is rotated to the 'CH'-edge as a result of Watson-Crick interaction, NucleicAcids Research, Apr. 30, 43(11):5275-83, Full text | |||||
PMID: 25934805 IF:9,1 | ||||||
64. | Hirsch, M. & Helm, M. (2015) Live cell imaging of duplex siRNA intracellular trafficking. NucleicAcids Research, Apr. 13, 43(9):4650-60, Full text | |||||
PMID: 25870407 IF:9,1 | ||||||
63. | Rimbach, K., Kaiser, S., Helm, M., Dalpke, A.H., Eigenbrod, T. (2015).2'-O-Methylation within Bacterial RNA Acts as Suppressor of TLR7/TLR8 Activation in Human Innate Immune Cells.Journale of innate immunity. Mar. 20, 7(5):482-93, Fulltext | |||||
PMID: 25823462 IF:4,4 | ||||||
62. | Juedes, A., Ebert, F., Baer, C., Thuering, K. L., Harrer, A., Klassen, R., Helm, M. & Schaffrath, R. (2015).Urmylationand tRNAthiolation functions of ubiquitin-like Uba4 Urm1 systems are conserved from yeast to man. FEBS letters, Mar. 03, 589(8):904-9, Full text | |||||
PMID:25747390 IF:9,1 | ||||||
61. | Klassen, R., Grunewald, P., Thuering, K. L., Eichler, C., Helm, M., & Schaffrath, R. (2015).Loss of Anticodon Wobble Uridine Modifications Affects tRNALys Function and Protein Levels in Saccharomyces cerevisiae.PLoSONE,Mar 6;10(3):e0119261, Fulltext | |||||
PMID:25747122 IF:3,2 | ||||||
60. | Abdel-Fattah, W., Jablownski, D., Di Santo, R., Thuering, K.L., Scheidt, V., Hammermeister, A., Have, S. t., Helm, M., Schaffrath, R., Stark, M.J.R. (2015). ”Phosphorylation of Elp1 by Hrr25 Is Required for Elongator-Dependent tRNA Modification in Yeast. PlosGen.Jan 8. 11(1):e1004931. Fulltext | |||||
PMID:25569479 IF:7,5 | ||||||
--2014-- | ||||||
-Originals- | -Reviews- | |||||
59. | Krieg, B., Hirsch, M., Scholz, E., Nuhn, L., Tabujew, I., Bauer, Hâ¦.,&Helm, M. (2014).”New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes. Pharmaceutical Research. Oct 09, 32(6):1957-74, Full text | R11 | Spenkuch, F., Motorin, Y., & Helm, M.(2014). Pseudouridine: Still mysterious, but never a fake (uridine)!.RNA biology, 11(12):1540-54, Full text | |||
PMID:25488263 IF:3,4 | PMID: 25616362 IF:5,0 | |||||
58. | Spenkuch, F., Hinze, G., Kellner, S., Kreutz, C., Micura, R., Basché, T. & Helm, M. (2014).”Dye label interference with RNA modification reveals 5-fluorouridine as non-covalent inhibitor. NucleicAcids Research. Oct 09, 42(20):12735-45, Full text | R10 | Helm, M. & Alfonzo, JD. (2014). "Posttranscriptional RNA Modifications: Playing Metabolic Games in a Cell's Chemical Legoland. Chem. Biol., Feb. 20, 21(2):174-85, Full text | |||
PMID:25300485 IF:9,1 | PMID: 24315934 IF:6,7 | |||||
57. | Kellner, S., Ochel, A., Thüring, K., Spenkuch, F., Neumann, J., Sharma, S., Entian, K.D., Schneider, D. & Helm, M. (2014).”Absolute and relative quantification of RNA modifications via biosynthetic isotopomers. NucleicAcids Research. Aug 16., 42(18):e142, Full text | |||||
PMID:25129236 IF:9,1 | ||||||
56. | Blanco, S., Dietmann, S., Flores, J.V., Hussain, S., Kutter, C., Humphreys, P., Lukk, M., Lombard, P., Treps, L. Popis, M., Kellner, S., Hölter, S.M., Garret, L., Wurst, W., Becker, L., Klopstock, T., Fuchs, H., Gailus-Durner, V., Hrabe de Angelis, M., Karadottir, R.T., Helm, M., Ule, J., Gleeson, J.G., Odom, D.T., Frye, M. (2014).”Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. TheEMBO Journal, Jul 25., 33(18):2020-39, Full text | |||||
PMID: 25063673 IF:10,4 | ||||||
55. | Kaiser, S., Rimbach, K., Eigenbrod, T., Dalpke, A.H. & Helm, M. (2014)."A modified dinucleotide motif specifies tRNA recognition by TLR7." RNA Sep.20(9):1351-5, Full text | |||||
PMID:25051971 IF:4,9 | ||||||
54. | Fritz, T. Hirsch, M. Richter, F.C., Müller, S.S., Hofmann, A.M., Rusitzka, K.A., Markl, J., Massing, U., Frey, H. Helm, M. (2014)."Click modification of multifunctional liposomes bearing hyperbranched polyether chains." Biomacromolecules, Jul 14., 15(7):2440-8, Full text | |||||
PMID: 24805163 IF:5,8 | ||||||
53. | KotaskovaM., Osman Oglou O., Helm, M. (2014) "Synthesis of new asymmetric xanthene dyes via catalyst-free SNAr with sulfur nucleophiles" Organic & Biomolecular Chemistry, Jun 21., 12(23):3816-20, Full text | |||||
PMID: 24802552 IF:3,6 | ||||||
52. | Shanmugam, R., Aklujkar, M., Schäfer, M., Reinhardt, R., Nickel, O., Reuter, G., Lovley, D.R., Ehrenhofer-Murray, A., Nellen, W., Ankri, S., Helm, M. et al.(2014). "The Dnmt2 RNA methyltransferase homolog of Geobactersulfurreducens specifically methylatestRNA-Glu."Nucleic Acids Research, Apr 7., 42(10):6487-96, Full text | |||||
PMID: 24711368IF:9,1 | ||||||
51. | Tabujew, I., Freidel, C., Krieg, B., Helm, M., Koynov, K., Müllen, K., Peneva, K. (2014). "The Guanidinium Group as a Key Part of Water-Soluble Polymer Carriers for siRNA Complexation and Protection against Degradation." Macromolecular rapid communications, Apr 4.,35(13):1191-7, Full Text | |||||
PMID: 24700561 IF:4,9 | ||||||
50. | Buchhaupt, M., Sharma,S., Kellner, S., Oswald, S.,Paetzold, M., Pfeifer, C., Watzinger, P., Schraeder, J., Helm, M., Entian, K.D.(2014). "Partial Methylation at Am100 in 18S rRNA of Baker's Yeast Reveals Ribosome Heterogeneity on the Level of Eukaryotic rRNA Modification." PLoSOne, Feb 28, 9(2):e89640, Full text | |||||
PMID: 24586927 IF:3,2 | ||||||
49. | Kellner, S., Neumann, J., Rosenkranz, D., Lebedeva, S., Ketting, R.F., Zischler, H., Schneider, D., & Helm, M.*(2014). "Profiling of RNA modifications by multiplexed stable isotope labelling." ChemicalCommunications.(Cambridge, England), Apr 4., 50(26):3516-8, Full text | |||||
PMID: 24567952 IF:6,8 | ||||||
--2013-- | ||||||
-Originals- | -Reviews- | |||||
48. | Kellner, S., Kollar, L. B., Ochel, A., Ghate, M. & Helm, M. (2013). "Structure-Function Relationship of Substituted Bromomethylcoumarins in Nucleoside Specificity of RNA Alkylation." PLoSOne. (Public Library of science), Jul 3., 8(7):e67945, Full text | |||||
PMID: 23844135 IF:3,2 | ||||||
47. | Machnicka, M. A., Milanowska, K., Osman Oglou, O., Purta, E., Kurkowska, M., Olchowik, A., Januszewski, W., Kalinowski, S., Dunin-Horkawicz, S., Rother, K., Helm, M., Bujnicki, J. M. & Grosjean, H. (2012). "MODOMICS: a database of RNA modification pathways--2012 update." Nucleic Acids Research, Oct 30, 41(Database issue): D262-7, Full text | |||||
PMID: 23118484 IF:9,1 | ||||||
--2012-- | ||||||
-Originals- | -Reviews- | |||||
46. | Seidu-Larry, S., Krieg, B., Hirsch, M., Helm, M. & Domingo, O. (2012). "A modified guanosine phosphoramidite for click functionalization of RNA on the sugar edge." ChemicalCommunications (Cambridge, England), Nov 18., 48(89):11014-6, Full text | R9 | Dalpke, A. & Helm, M. (2012). "RNA mediated Toll-like receptor stimulation in health and disease."RNA Biol, Jun., 9(6):828-42, Full text | |||
PMID: 23037931 IF:6,8 | PMID: 22617878 IF:5,0 | |||||
45. | Tuorto, F., Liebers, R., Musch, T., Schaefer, M., Hofmann, S., Kellner, S., Frye, M., Helm, M., Stoecklin, G. & Lyko, F. (2012)."RNA cytosine methylation by Dnmt2 and NSun2 promotes tRNA stability and protein synthesis." Nature Structural & Molecular Biology. Sep, 19(9):900-5, Full Text | |||||
PMID: 22885326 IF:13,3 | ||||||
44. | Jurkowski, T. P., Shanmugam, R., Helm, M. & Jeltsch, A. (2012)."Mapping the tRNA Binding Site on the Surface of Human DNMT2 Methyltransferase." Biochemistry, Jun 5., 51(22):4438-44, Full text | |||||
PMID: 22591353 IF:3,0 | ||||||
43. | Sencilo, A., Paulin, L., Kellner, S., Helm, M. & Roine, E. (2012). "Related haloarchaeal pleomorphic viruses contain different genome types." Nucleic Acids Research, Jul, 40(12):5523-34, Full Text | |||||
PMID: 22396526 IF:9,1 | ||||||
42. | Nuhn, L., Hirsch, M., Krieg, B., Koynov, K., Fischer, K., Schmidt, M., Helm, M. & Zentel, R. (2012)."Cationic Nanohydrogel Particles as Potential siRNA Carriers for Cellular Delivery." ACS Nano, Mar 27., 6(3):2198-214, Full text | |||||
PMID: 22381078 IF:12,9 | ||||||
41. | Gehrig, S., Eberle, M. E., Botschen, F., Rimbach, K., Eberle, F., Eigenbrod, T., Kaiser, S., Holmes, W. M., Erdmann, V. A., Sprinzl, M., Bec, G., Keith, G., Dalpke, A. H. & Helm, M.(2012)."Identification of modifications in microbial, native tRNA that suppress immunostimulatory activity." The Journal of Experimental Medicine, Feb 13., 209(2):225-33, Full text | |||||
PMID: 22312113 IF:12,5 | ||||||
40. | Hirsch, M., Strand, D. & Helm, M.(2012)."Dye selection for live cell imaging of intact siRNA." BiologicalChemistry , Jan, 393(1-2):23-3, Full text | |||||
PMID: 22628296 IF:3,3 | ||||||
--2011-- | ||||||
-Originals- | -Reviews- | |||||
39. | Kobitski, A. Y., Hengesbach, M., Seidu-Larry, S., Dammertz, K., Chow, C. S., van Aerschot, A., Nienhaus, G. U. & Helm, M. (2011). "Single-Molecule FRET Reveals a Cooperative Effect of Two Methyl Group Modifications in the Folding of Human Mitochondrial tRNA(Lys)."Chemistry & Biology , Jul 19., 18(7):928-36, Full text | R8 | Motorin, Y. & Helm, M.* (2011). "RNA nucleotide methylation." Wiley Interdiscip Rev RNA, Sep.-Oct., 2(5):611-31, Full text | |||
PMID: 21802013 IF:6,7 | PMID: 21823225 IF: 6,0 | |||||
38. | Kellner, S., Seidu-Larry, S., Burhenne, J., Motorin, Y. & Helm, M. (2011). "A multifunctional bioconjugate module for versatile photoaffinity labeling and click chemistry of RNA."NucleicAcids Research, Sep 1., 39(16):7348-60, Full text | R7 | Behm-Ansmant, I., Helm, M. & Motorin, Y. (2011). "Use of specific chemical reagents for detection of modified nucleotides in RNA."J NucleicAcids, Apr. 13, 2011:408053, Full text | |||
PMID: 21646334 IF:9,1 | PMID: 21716696 IF: 8,0 | |||||
37. | Nguyen, T. H., Steinbock, L. J., Butt, H. J., Helm, M. & Berger, R. (2011). "Measuring single small molecule binding via rupture forces of a split aptamer." Journal of the American ChemicalSociety , Feb 23., 133(7):2025-7, Full text | |||||
PMID: 21287983 IF:12,1 | ||||||
36. | Dammertz, K., Hengesbach, M., Helm, M., Nienhaus, G. U. & Kobitski, A. Y. (2011). "Single-molecule FRET studies of counterion effects on the free energy landscape of human mitochondriallysine tRNA." Biochemistry , Apr 19., 50(15):3107-15, Full text | |||||
PMID: 21375355 IF:3,0 | ||||||
35. | Motorin, Y., Burhenne, J., Teimer, R., Koynov, K., Willnow, S., Weinhold, E. & Helm, M. (2011). "Expanding the chemical scope of RNA:methyltransferases to site-specific alkynylation of RNA for click labeling." Nucleic Acids Research , Mar, 39(5):1943-5, Full text | |||||
PMID: 21037259 IF:9,1 | ||||||
--2010-- | ||||||
-Originals- | -Reviews- | |||||
34. | Schaefer, M., Pollex, T., Hanna, K., Tuorto, F., Meusburger, M., Helm, M. & Lyko, F. (2010). "RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage." Genes & Development , Aug 1., 24(15):1590-5, Full Text | R6 | Motorin, Y. & Helm, M.* (2010). "tRNAstabilization by modified nucleotides." Biochemistry, Jun. 22, 49(24):4934-44. | |||
PMID: 20679393 IF:10,8 | PMID: 20459084 IF: 3,0 | |||||
33. | Hengesbach, M., Voigts-Hoffmann, F., Hofmann, B. & Helm, M. (2010). "Formation of a stalled early intermediate of pseudouridine synthesis monitored by real-time FRET." RNA, Mar, 16(3):610-2, Full Text | R4 | Kellner, S.,Burhenne, J. & Helm, M.* (2010). "Detection of RNA modifications." RNABiol, Mar.-Apr., 7(2):237-47. | |||
PMID: 20106954 IF:4,9 | PMID:20224293 IF: 3,2 | |||||
32. | Tovy, A., Siman Tov, R., Gaentzsch, R., Helm, M. & Ankri, S. (2010). "A new nuclear function of the Entamoebahistolytica glycolytic enzyme enolase: the metabolic regulation of cytosine-5 methyltransferase 2 (Dnmt2) activity." PLoSPathogens , Feb 19., 6(2):e1000775, Full text | R4 | Motorin, Y.,Lyko, F. & Helm, M.* (2010). "5-methylcytosine in RNA: Detection, enzymatic formation and biological functions." Nucleic Acids Res, March, 38(5):1415-30, Full text | |||
PMID: 20174608 IF:7,6 | PMID: 20007150 IF: 9,1 | |||||
--2009-- | ||||||
-Originals- | -Reviews- | |||||
31. | Fuest, C., Bankstahl, M., Winter, P., Helm, M., Pekcec, A. & Potschka, H. (2009). "In vivo down-regulation of mouse brain capillary P-glycoprotein: a preliminary investigation." NeuroscienceLetters , Oct 16., 464(1):47-51, Full text | R3 | Helm, M.*,Kobitski, A. & Nienhaus, G. (2009). "Single-molecule Förster resonance energy transfer studies of RNA structure, dynamics and function."BiophysicalReviews, Nov. 10,1(4): 161-176 | |||
PMID: 19679165 IF:2,0 | DOI: 10.1007/s12551-009-0018-3 IF: 3,0 | |||||
30. | Hayrapetyan, A., Grosjean, H. & Helm, M. (2009). "Effect of a quaternary pentamine on RNA stabilization and enzymatic methylation." BiologicalChemistry , Sep, 390(9):851-6, Full text | |||||
PMID: 19558320 IF:3,3 | ||||||
29. | Hirsch, M., Ziroli, V., Helm, M. & Massing, U. (2009). "Preparation of small amounts of sterile siRNA-liposomes with high entrapping efficiency by dual asymmetric centrifugation (DAC)." Journal of Controlled Release , Apr 2.,135(1):80-8, Full text | |||||
PMID: 19124051 IF:7,7 | ||||||
--2008-- | ||||||
-Originals- | -Reviews- | |||||
28. | Jurkowski, T. P., Meusburger, M., Phalke, S., Helm, M., Nellen, W., Reuter, G. & Jeltsch, A. (2008). "Human DNMT2 methylatestRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism." RNA , Aug, 14(8):1663-70, Full text | R2 | Kobitski, A. Y., Nierth, A., Hengesbach, M., Jaschke, A., Helm, M. & Nienhaus, G. U.* (2008). "Exploring the folding free energy landscape of small RNA molecules by single-pair Förster resonance energy transfer." Biophys. Rev.Lett, Oct., 3(4): 439-457., | |||
PMID: 18567810 IF:4,9 | DOI: 10.1142/S1793048008000873 IF: 3,0 | |||||
27. | Kobitski, A. Y., Hengesbach, M., Helm, M. & Nienhaus, G. U. (2008). "Sculpting an RNA conformational energy landscape by a methyl group modification--a single-molecule FRET study." AngewandteChemie (International Ed in Englisch) 47(23):4326-30, Full text | |||||
PMID: 18449867 IF:11,3 | ||||||
26. | Steinbock, L. J. & Helm, M. (2008). "Wavelength dependence of photoinducedmicrocantilever bending in the UV-VIS range." Sensors 8(1):23-34, Full text | |||||
doi:10.3390/s8010023 IF:2,3 | ||||||
25. | Hengesbach, M., Meusburger, M., Lyko, F. & Helm, M. (2008). "Use of DNAzymes for site-specific analysis of ribonucleotide modifications." RNA , Jan, 14(1):180-7, Full text | |||||
PMID: 17998290 IF:4,9 | ||||||
--2007-- | ||||||
-Originals- | -Reviews- | |||||
24. | Voigts-Hoffmann, F., Hengesbach, M., Kobitski, A. Y., van Aerschot, A., Herdewijn, P., Nienhaus, G. U. & Helm, M. (2007). "A methyl group controls conformational equilibrium in human mitochondrial tRNA(Lys)." Journal of the American Chemical Society, Nov 7., 129(44):13382-3, Full text | |||||
PMID: 17941640 IF:12,1 | ||||||
23. | Järve, A., Müller, J., Kim, I. H., Rohr, K., MacLean, C., Fricker, G., Massing, U., Eberle, F., Dalpke, A., Fischer, R., Trendelenburg, M. F. & Helm, M. (2007). "Surveillance of siRNA integrity by FRET imaging." Nucleic Acids Research, 35(18):e124, Full text | |||||
PMID: 17890733 IF:9,1 | ||||||
22. | Wehrmeister, J., Fuss, A., Saurenbach, F., Berger, R. & Helm, M. (2007). "Readout of micromechanical cantilever sensor arrays by Fabry-Perot interferometry." TheReview of ScientificInstruments, Oct, 78(10):104105, Full text | |||||
PMID: 17979440 IF:1,6 | ||||||
21. | Kobitski, A. Y., Nierth, A., Helm, M., Jaschke, A. & Nienhaus, G. U. (2007). "Mg2+-dependent folding of a Diels-Alderase ribozyme probed by single-molecule FRET analysis." NucleicAcids Research, 35(6):2047-5, Full text | |||||
PMID: 17344321IF:9,1 | ||||||
--2006-- | ||||||
-Originals- | -Reviews- | |||||
20. | Maniura-Weber, K., Helm, M., Engemann, K., Eckertz, S., Mollers, M., Schauen, M., Hayrapetyan, A., von Kleist-Retzow, J. C., Lightowlers, R. N., Bindoff, L. A. & Wiesner, R. J. (2006). "Molecular dysfunction associated with the human mitochondrial 3302A>G mutation in the MTTL1 (mt-tRNALeu(UUR)) gene." NucleicAcids Research 34(22):6404-15, Full text | R1 | Helm, M.*(2006). "Post-transcriptional nucleotide modification and alternative folding of RNA." Nucleic Acids Res, Feb. 1,34(2):721-33, Full text | |||
PMID: 17130166 IF:9,1 | PMID:16452298 IF: 9,1 | |||||
--2005-- | ||||||
-Originals- | -Reviews- | |||||
19. | Möllers, M., Maniura-Weber, K., Kiseljakovic, E., Bust, M., Hayrapetyan, A., Jaksch, M., Helm, M., Wiesner, R. J. & von Kleist-Retzow, J. C. (2005). "A new mechanism for mtDNA pathogenesis: impairment of post-transcriptional maturation leads to severe depletion of mitochondrial tRNASer(UCN) caused by T7512C and G7497A point mutations." Nucleic Acids Research , Sep 30., 33(17):5647-58, Full text | |||||
PMID: 16199753 IF:9,11 | ||||||
18. | Kurschat, W. C., Müller, J., Wombacher, R. & Helm, M. (2005). "Optimizing splinted ligation of highly structured small RNAs." RNA , Dec, 11(12):1909-14, Full text | |||||
PMID: 16251384IF:4,9 | ||||||
17. | Helm, M., Petermeier, M., Ge, B., Fiammengo, R. & Jäschke, A. (2005). "Allosterically activated Diels-Alder catalysis by a ribozyme." Journal of the American ChemicalSociety , Aug 3, 127(30):10492-3, Full text | |||||
PMID: 16045328 IF:12,1 | ||||||
16. | Helm, M., Servant, J. J., Saurenbach, F. & Berger, R. (2005). "Read-out of micromechanical cantilever sensors by phase shifting interferometry." Applied Physics Letters 87(6). | |||||
doi:10.1063/ 1.2008358 IF:3,3 | ||||||
--2004-- | ||||||
-Originals- | -Reviews- | |||||
15. | Sissler, M., Helm, M., Frugier, M., Giege, R. & Florentz, C. (2004). "Aminoacylation properties of pathology-related human mitochondrial tRNA(Lys) variants." RNA, May, 10(5):841-53 | |||||
PMID: 15100439 IF:4,9 | ||||||
14. | Helm, M.& Attardi, G. (2004). "Nuclear control of cloverleaf structure of human mitochondrial tRNA(Lys)." Journal of MolecularBiology , Mar 26., 337(3):545-60, Full text | |||||
PMID: 15019776 IF:3,0 | ||||||
13. | Asin-Cayuela, J., Helm, M. & Attardi, G. (2004). "A monomer-to-trimer transition of the human mitochondrial transcription termination factor (mTERF) is associated with a loss of in vitro activity." Journal of BiologicalChemistry , Apr 9., 279(15):15670-7, Full text | |||||
PMID: 14744862 IF:4,6 | ||||||
--2001-- | ||||||
-Originals- | -Reviews- | |||||
12. | Schiffer, S., Helm, M., Theobald-Dietrich, A., Giege, R. & Marchfelder, A. (2001). "The plant tRNA 3' processing enzyme has a broad substrate spectrum." Biochemistry , Jul 27., 40(28):8264-72, Full text | |||||
PMID: 11444972 IF:3,0 | ||||||
11. | Helm, M., Kopka, M. L., Sharma, S. K., Lown, J. W. & Giege, R. (2001). "RNase activity of a DNA minor groove binder with a minimalist catalytic motif from RNase A." Biochemical andBiophysical Research Communications , Mar, 281(5):1283-90, Full text | |||||
PMID: 11243875 IF:2,3 | ||||||
--2000-- | ||||||
-Originals- | -Reviews- | |||||
10. | Helm, M., Brule, H., Friede, D., Giege, R., Putz, D. & Florentz, C. (2000). "Search for characteristic structural features of mammalian mitochondrial tRNAs." RNA , Oct, 6(10):1356-7, Full text | |||||
PMID: 11073213IF:4,9 | ||||||
--1999-- | ||||||
-Originals- | -Reviews- | |||||
9. | Helm, M., Giege, R. & Florentz, C. (1999). "A Watson-Crick base-pair-disrupting methyl group (m1A9) is sufficient for cloverleaf folding of human mitochondrial tRNALys." Biochemistry , Oct 5., 38(40):13338-46, Full text | |||||
PMID: 10529209 IF:3,0 | ||||||
8. | Vlasov, A. V., Helm, M., Naumov, V. A., Breusov, A. A., Buneva, V. N., Florentz, C., Giege, R. & Nevinskii, G. A. (1999). "[Features of tRNA hydrolysis by autoantibodies from blood serum of patients with certain autoimmune and virus diseases]." MolekuliarnaiaBiologiia (Mosk) , Sep -Oct, 33(5):866-72 | |||||
PMID: 10579192 IF:N/A | ||||||
7. | Vlassov, A. V., Helm, M., Florentz, C., Naumov, V. A., Breusov, A. A., Buneva, V. N., Giege, R. & Nevinsky, G. A. (1999). "Variability of Substrate Specificity of Serum Antibodies Obtained from Patients with Different Autoimmune and Viral Diseases in Reaction of tRNA Hydrolysis." RussianJournal of Immunologie , Apr, 4(1):25-32 | |||||
PMID: 12687113 IF:N/A | ||||||
6. | Helm, M., Brule, H., Giege, R. & Florentz, C. (1999). "More mistakes by T7 RNA polymerase at the 5' ends of in vitro-transcribed RNAs." RNA , May, 5(5):618-21, Full text | |||||
PMID: 10334331 IF:4,9 | ||||||
5. | Helm, M., Florentz, C., Chomyn, A. & Attardi, G. (1999). "Search for differences in post-transcriptional modification patterns of mitochondrial DNA-encoded wild-type and mutant human tRNALys and tRNALeu(UUR)." NucleicAcids Research , Feb 1., 27(3):756-63, Full text | |||||
PMID: 9889270 IF:9,1 | ||||||
--1998-- | ||||||
-Originals- | -Reviews- | |||||
4. | Degoul, F., Brule, H., Cepanec, C., Helm, M., Marsac, C., Leroux, J., Giege, R. & Florentz, C. (1998). "Isoleucylation properties of native human mitochondrial tRNAIle and tRNAIle transcripts. Implications for cardiomyopathy-related point mutations (4269, 4317) in the tRNAIle gene." Human Molecular Genetics , Mar, 7(3):347-54, Full text | |||||
PMID: 9466989 IF:6,4 | ||||||
3. | Vlassov, A., Florentz, C., Helm, M., Naumov, V., Buneva, V., Nevinsky, G. & Giege, R. (1998). "Characterization and selectivity of catalytic antibodies from human serum with RNase activity." NucleicAcids Research, Dec 1., 26(23):5243-50, Full text | |||||
PMID: 9826744 IF:9,1 | ||||||
2. | Frugier, M., Helm, M., Felden, B., Giege, R. & Florentz, C. (1998). "Sequences outside recognition sets are not neutral for tRNAaminoacylation. Evidence for nonpermissive combinations of nucleotides in the acceptor stem of yeast tRNAPhe." TheJournal of BiologicalChemistry , May 8., 273(19):11605-10, Full text | |||||
PMID: 9565578 IF:4,8 | ||||||
1. | Helm, M., Brule, H., Degoul, F., Cepanec, C., Leroux, J. P., Giege, R. & Florentz, C. (1998). "The presence of modified nucleotides is required for cloverleaf folding of a human mitochondrial tRNA." NucleicAcids Research ,Apr 1., 26(7):1636-43, Full text | |||||
PMID: 9512533 IF:9,1 | ||||||