Our Research Group was active until my retirement in Sept. 2017. However, these pages are still maintained for those interested in polychaete and lipoprotein Research.
My main research interests are the structure and function of animal lipoproteins and the lipid transport in invertebrates. Lipoproteins are not only important for the general lipid supply to various cells and tissues, but also during reproduction of ovioparous animals. Our main model organisms are the polychaetes, a large group of marine annelids and their reproductive physiology and we are also work on crustaceans and more recently, chelicerates.
Our work involved the isolation of lipoproteins by density gradient centrifugation and biochemical methods for the characterization of lipoproteins. We use labeled proteins to study lipoprotein uptake by fluorescence microscopy, the analysis of lipoprotein bound lipids by HPLC and mass spectrometry and the characterization of lipoproteins and their receptors using chromatographic, electron microscopic and molecular techniques.
For more information follow the "Research" link above.
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| Oocytes after uptake of FITC labelled yolk Protein | Endocytotic vesicles at an oocyte surface loaded with DiI and DiO labeled lipoprotein | Colorfull lipoproteins in the lobster hemolymph |
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| Platynereis dumerilii | lipid droplets in the epidermis of Platynereis |