Prof. Dr. Ute A. Hellmich

Short Bio: Ute Hellmich carried out her undergraduate studies in biochemistry at the Goethe-University Frankfurt and also collected research experience through multiple research internships, including at Imperial College London. For her PhD thesis, she joined the research group of Prof. Clemens Glaubitz in Frankfurt to study bacterial membrane protein dynamics by solid-state NMR spectroscopy. In the framework of this highly interdisciplinary project, she also worked at the University of Cambridge Department of Pharmacology sponsored by an EMBO short term fellowship. For her post-doc, she joined the laboratory of Prof. Rachelle Gaudet at Harvard University to work on eukaryotic ion channels funded by an EMBO long-term fellowship. In 2015, she started her group as a junior professor for membrane biochemistry at the Johannes Gutenberg-University Mainz. In 2020, she was awarded tenure. The lab focusses on elucidating molecular mechanisms of bacterial multidrug resistance, the (dis)similarities between human and parasitic ion channels and the structural basis of lipid/ligand interactions and allosteric regulation of complex membrane proteins from microorganism to man.


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Awards and Recognitions (Selection)

2020 - Recipient of a Boehringer Ingelheim Stiftung Exploration Grant for outstanding junior researchers in chemistry, biology or medicine

2019 - Hoechst Dozentenpreis der Aventis Foundation und des Fonds der Chemischen Industrie

2018 - Chair of the German Chemical Society (GDCh) Chapter Mainz-Wiesbaden (with Prof. Eva Rentschler)

2018 - Nomination for the Alexander M. Cruickshank Award, Gordon Research Conference "Drug Metabolism"

2018 - Elected onto the FEBS ABC Conference Scientific Advisory Board

2017 - Fulbright-Cottrell Award for Excellence in Research and Teaching

2016 - Award for best Presentation, Bioorganische Chemie Symposium, Jena

2015 - Chair, Gordon Research Seminar "Mechanism of Membrane Transport"

2012-2014 EMBO Long Term Award for Harvard University, USA

2006- EMBO Short-term Fellowship for Cambridge University, UK


Most important papers

Dietschreit et al (2020) Angewandte Chemie Int. Ed. Engl., accepted, DOI: 10.1002/anie.202000539

Millies et al (2019) J. Med. Chem. 62(24):11359-11382

Heiby*, Goretzki* et al (2019) Nature Communications, 10(1):4378 (*contributed equally)

Viet*, Wagner* et al (2019) Structure, 27(8):1246-1257 (*contributed equally)

Wagner et al. (2019) Angewandte Chemie Int. Ed. Engl., 58(11):3640-4

Goretzki et al., (2018)  Structure, 26(12):1583-1593

Schirmeister et al. (2016) J. Am. Chem. Soc., 138(27):8332-5

Hellmich et al. (2013) Proc. Nat. Acad. Sci. USA 110(38):15253-8

Garcia-Elias et al. (2013) Proc. Nat. Acad. Sci. USA 110(23):9553-8

Hellmich et al. (2012) J. Am. Chem. Soc., 134(13):5857-62

Ulrich*, Hellmich* et al. (2011) Nature Chem. Biol. 7(5):263-70 (*contributed equally)

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