Jun.-Prof. Dr. Ute A. Hellmich

Short Bio: Ute Hellmich was born in Heidelberg in 1981. She carried out her undergraduate studies in biochemistry at the Goethe-University Frankfurt. During this time, she also collected research experience through multiple research internships, including in the laboratory of Prof. Howard Morris and Prof. Anne Dell at Imperial College London. For her PhD thesis, she joined the research group of Prof. Clemens Glaubitz in Frankfurt to study bacterial membrane protein dynamics by solid-state NMR spectroscopy. In the framework of this highly interdisciplinary project, she also worked at the University of Cambridge Department of Pharmacology sponsored by an EMBO short term fellowship. For her post-doc, she joined the laboratory of Prof. Rachelle Gaudet at Harvard University to work on eukaryotic ion channels funded by an EMBO long-term fellowship. Since 2015, she holds a junior professorship for membrane biochemistry at the Johannes Gutenberg-University Mainz. She also is a guest scientist at the Centre of Biomolecular Magnetic Resonance  (BMRZ) at the Goethe University Frankfurt. The lab focusses on elucidating molecular mechanisms of bacterial multidrug resistance, the (dis)similarities between human and parasitic ion channels and the structural basis of lipid/ligand interactions and allosteric regulation of complex membrane proteins from microorganism to man.

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Awards and Recognitions (Selection)

2018 - Chair of the German Chemical Society (GDCh) Chapter Mainz-Wiesbaden (with Prof. Eva Rentschler)

2018 - Nomination for the Alexander M. Cruickshank Award, Gordon Research Conference "Drug Metabolism"

2017 - Fulbright-Cottrell Award for Excellence in Research and Teaching

2017 - Elected onto the FEBS ABC Scientific Advisory Board

2016 - Award for best Presentation, Bioorganische Chemie Symposium, Jena

2015 - Chair, Gordon Research Seminar "Mechanism of Membrane Transport"

2012-2014 EMBO Long Term Award for Harvard University, USA

2006- EMBO Short-term Fellowship for Cambridge University, UK


Most important papers

Wagner et al. (2019) Angewandte Chemie Int. Ed., accepted

Goretzki et al., (2018)  Structure, 26(12):1583-1593

Preveti et al. (2017) J. Med. Chem. 60(16):6911-6923

Schirmeister et al. (2016) J. Am. Chem. Soc., 138(27):8332-5.

Hellmich et al. (2013) Proc. Nat. Acad. Sci. USA 110(38):15253-8

Garcia-Elias et al. (2013) Proc. Nat. Acad. Sci. USA 110(23):9553-8

Hellmich et al. (2012) J. Am. Chem. Soc., 134(13):5857-62.

Ulrich*, Hellmich* et al. (2011) Nature Chem. Biol. 7(5):263-70. (*contributed equally)

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