Publications 2015

Philipp Heller,† Nicole Mohr,† Alexander Birke, Benjamin Weber, Angelika Reske-Kunz, Matthias Bros, Matthias Barz
Directed Interactions of Block Copolypept(o)ides with Mannose-binding Receptors: PeptoMicelles Targeted to Cells of the Innate Immune System
Macromolecular Bioscience 15 (1), 63–73 (2015);
doi:10.1002/mabi.201400417

Achim T. Reibel, Sophie S. Müller, Stefanie Pektor, Nicole Bausbacher, Matthias Miederer, Holger Frey, Frank Rösch
Fate of Linear and Branched Polyether-Lipids In Vivo in Comparison to Their Liposomal Formulations by 18F-Radiolabeling and Positron Emission Tomography
Biomacromolecules 16 (3), 842–851 (2015);
doi:10.1021/bm5017332

Christian Hörtz, Alexander Birke, Leonard Kaps, Sandra Decker, Eva Wächtersbach, Karl Fischer, Detlef Schuppan, Matthias Barz, Manfred Schmidt
Cylindrical Brush Polymers with Polysarcosine Side Chains: A Novel Biocompatible Carrier for Biomedical Applications
Macromolecules 48 (7), 2074–2086 (2015);
doi:10.1021/ma502497x

Sandro Ebert, Markus B. Bannwarth, Anna Musyanovych, Katharina Landfester, Kerstin Münnemann
How morphology influences relaxivity – comparative study of superparamagnetic iron oxide–polymer hybrid nanostructures
Contrast Media & Molecular Imaging 10 (6), 456–464 (2015);
doi:10.1002/cmmi.1648

Laura K. Müller, Katharina Landfester
Natural liposomes and synthetic polymeric structures for biomedical applications
Biochem. Biophys. Res. Commun. 468 (3), 411–418 (2015);
doi:10.1016/j.bbrc.2015.08.088

Jan Kubach, Mario Hubo, Christiane Amendt, Christopher Stroh, Helmut Jonuleit
IgG1 anti-epidermal growth factor receptor antibodies induce CD8-dependent antitumor activity
Int. J. Cancer 136, 821–830 (2015);
doi:10.1002/ijc.29037

Matthew A. Hood, Umaporn Paiphansiri, David Schaeffel, Kaloian Koynov, Michael Kappl, Katharina Landfester, Rafael Muñoz-Espí
Hybrid Poly(urethane–urea)/Silica Nanocapsules with pH-Sensitive Gateways
Chem. Mater. 27 (12), 4311–4318 (2015);
10.1021/acs.chemmater.5b00690

David Schaeffel, Stoyan Yordanov, Roland Hinrich Staff, Andreas Kreyes, Yi Zhao, Manfred Schmidt, Katharina Landfester, Johan Hofkens, Hans-Jürgen Butt, Daniel Crespy, Kaloian Koynov
Fluorescence Correlation Spectroscopy in Dilute Polymer Solutions: Effects of Molar Mass Dispersity and the Type of Fluorescent Labeling
ACS Macro Lett. 4 (2), 171–176 (2015);
doi:10.1021/mz500638e

Jing Xie, Keita Nakai, Sayaka Ohno, Hans-Juergen Butt, Kaloian Koynov, Shin-ichi Yusa
Fluorescence Correlation Spectroscopy Monitors the Hydrophobic Collapse of pH-Responsive Hairy Nanoparticles at the Individual Particle Level
Macromolecules 48 (19), 7237–7244 (2015);
doi:10.1021/acs.macromol.5b01435

Sebastian Hartmann,+ Lutz Nuhn,+ Björn Palitzsch, Markus Glaffig, Natascha Stergiou, Bastian Gerlitzki, Edgar Schmitt, Horst Kunz, Rudolf Zentel
CpG-loaded Multifunctional Cationic Nanohydrogel Particles as Self-Adjuvanting Glycopeptide Antitumor Vaccines
Adv. Health Care 4, 522–527 (2015);
Doi:10.1002/adhm.201400460

Bettina Krieg, Markus Hirsch, Erik Scholz, Lutz Nuhn, Ilja Tabujew, Heiko Bauer, Sandra Decker, Andriy Khobta, Manfred Schmidt, Wolfgang Tremel, Rudolf Zentel, Kalina Peneva, Kaloian Koynov, A. James Mason, Mark Helm
New Techniques to Assess In Vitro Release of siRNA from Nanoscale Polyplexes
Pharm Res
 32, 19571974 (2015);
DOI:10.1007/s11095-014-1589-7

Kristof Tappertzhofen, Franziska Weiser, Evelyn Montermann, Angelika Reske-Kunz, Matthias Bros,* and Rudolf Zentel*
Poly-l-lysine-poly[HPMA] block copolymers obtained by RAFT-polymerisation as polyplex-transfection reagents with minimal toxicity
Macromol. Biosci. 15, 1159 –1173 (2015);
DOI:10.1002/mabi.201500022

E. Lepeltier, L. Nuhn, C.M. Lehr*, R. Zentel*,
Not just for tumor targeting: Unmet medical needs and opportunities for nanomedicine
Nanomedicine 10 (20), 3147-3166 (2015);
DOI:10.2217/NNM.15.132

Leonard Kaps, Lutz Nuhn, Misbah Aslam, Alexander Brose, Friedrich Foerster, Sebastian Rosigkeit, Patricia Renz, Rosario Heck, Yong Ook Kim, Ingo Lieberwirth, Detlef Schuppan* and Rudolf Zentel*
In Vivo Gene-Silencing in Fibrotic Liver by siRNA-Loaded Cationic Nanohydrogel Particles
Adv. Health Care Materials, 4, 2809 -2815 (2015);
doi:10.1002/adhm.201500826

S. Köhler, F. Schmid, G. Settanni,
The internal dynamics of fibrinogen and its implications for coagulation and adsorption
PLOS Computational Biology 11, e1004346
doi:10.1371/journal.pcbi.1004346 (2015)

O. Zupke, E. Distler, A. Jürchott, U. Paiphansiri, M. Dass, S. Thomas, U.F. Hartwig, M. Theobald, K. Landfester, V. Mailänder, W. Herr
“Nanoparticles and antigen-specific T-cell therapeutics: a comprehensive study on uptake and release”
Nanomedicine (Lond.) 2015, 10, 1063–1076

G. Baier, S. Winzen, C. Messerschmidt, S. Frank, M. Fichter, S. Gehring, V. Mailänder, K. Landfester
“Heparin-Based Nanocapsules as Potential Drug Delivery Systems”
Macromol. Biosci. 2015, 15, 765-776

B. Kang, P. Okwieka, S. Schöttler, S. Winzen, J. Langhanki, K.Mohr, T. Opatz, V. Mailänder, K. Landfester, F.R. Wurm
„Carbohydrate-Based Nanocarriers Exhibiting Specific Cell Targeting with Minimum Influence from the Protein Corona”
Angew. Chem. Internat. Ed. 2015, 54, 7436-7440

B. Kang, P. Okwieka, S. Schöttler, S. Winzen, J. Langhanki, K.Mohr, T. Opatz, V. Mailänder, K. Landfester, F.R. Wurm
„Kohlenhydrat-basierte Nanocarrier mit spezifischem Zell-Targeting und minimalem Einfluss durch die Proteinkorona“
Angew. Chem. 2015, 127, 7544 –7548

S. Lerch, S. Ritz, K. Bley, C. Messerschmidt, C.K. Weiss, A. Musyanovych, K. Landfester, V. Mailänder
“Nanoprobing the acidification process during intracellular uptake and trafficking”
Nanomedicine : nanotechnology, biology, and medicine 2015, 11, 1585-1596

Brüstle, T. Simmet, G.U. Nienhaus, K. Landfester, V. Mailänder
Hematopoietic and mesenchymal stem cells: polymeric nanoparticle uptake and lineage differentiation
Beilstein J. Nanotechnol. 2015, 6, 383-395.
doi:10.3762/bjnano.6.38

Fichter, M. Dedters, A. Pietrzak-Nguyen, L. Pretsch, C.U. Meyer, F. Zepp, G. Baier, K. Landfester, S. Gehring
Monophosphoryl lipid A coating of hydroxyethyl starch nanocapsules drastically increases uptake and maturation by dendritic cells while minimizing the adjuvant dosage
Vaccine 2015, 7, 838-846
doi: 10.1016/j.vaccine.2014.12.072

Winzen, S. Schoettler, G. Baier, C. Rosenauer, V. Mailänder, K. Landfester, K. Mohr
Complementary analysis of the hard and soft protein corona: sample preparation critically effects corona composition
Nanoscale 2015, 7, 2992-3001
doi: 10.1039/c4nr05982d

Piradashvili, M. Fichter, K. Mohr, S. Gehring, F.R. Wurm, K. Landfester
Biodegradable Protein Nanocontainers
Biomacromolecules 2015, 16, 815-821
doi: 10.1021/bm5016915

B. Kang, P. Okwieka, S. Schöttler, O. Seifert, R. Kontermann, K. Pfizenmaier, A. Musyanovych, R. Meyer, M. Diken, U. Sahin, V. Mailänder, F.R. Wurm, K. Landfester
Tailoring the stealth properties of biocompatible polysaccharide nanocontainers.
Biomaterials 2015, 49, 125-134
doi:10.1016/j.biomaterials.2015.01.042

Ritz, S. Schöttler, N. Kotman, G. Baier, A. Musyanovych, J. Kuharev, K. Landfester, H. Schild, O. Jahn, S. Tenzer, V. Mailänder
Protein corona of nanoparticles: distinct proteins regulate the cellular uptake
Biomacromolecules 2015, 16, 1311-1321
doi: 10.1021/acs.biomac.5b00108

Peters T1, Grunewald C, Blaickner M, Ziegner M, Schütz C, Iffland D, Hampel G, Nawroth T, Langguth P.
Cellular uptake and in vitro antitumor efficacy of composite liposomes for neutron capture therapy
Radiation Oncology 10:15 (2015);
DOI: 10.1186/s13014-015-0342-7